Immunohistochemistry (Paraffin): 1:100-1:1000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:10,000
Reviews / Ratings
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Description
Lamin B1 Polyclonal Antibody. Lamin B1 is a part of a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domain