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Description
REEP1/REEP2 Monoclonal Antibody (S326D-29). The REEP family are transmembrane proteins that interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. REEP2 is an integral membrane protein expressed in taste cells. Unlike its counterpart REEP1, REEP2 does not increase cell surface expression to sweet receptors, but instead alters their spatial organization. REEP1 protein is a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder.
Immunogen
n/a
Other Names
Receptor expression-enhancing protein 2, C5orf19, SGC32445, LOC682105