Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000
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Description
S100A6 Monoclonal Antibody (OTI5A10). The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Immunogen
n/a
Other Names
2A9, 5B10, CABP, CACY, PRA, MLN 4, S100 calcium-binding protein A6 (calcyclin), calcyclin, growth factor-inducible protein 2A9, prolactin receptor-associated protein, protein S100-A6