Recombinant Mouse Proto-oncogene tyrosine-protein kinase receptor Ret (Ret), partial
Description
MW: 119,469 Da. Purity >85% (SDS-PAGE). This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neopl