Recombinant Mouse PSGL-1 / CD162 / SELPLG Protein (Fc tag)
Description
MW: 41,842 Da. Purity >85 % as determined by SDS-PAGE. Background: P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein, expressed on leukocytes and platelets as a homodimer of two disulfide-linked subunits of ~120 kD. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the n
Size
0.05 mg, 0.1 mg
Concentration
n/a
Applications
The secreted recombinant mouse SELPLG/Fc is a disulfide-linked homodimer. The reduced monomer comprises 531 amino acids and has a calculated molecular mass of 57.4 kDa. As a result of glycosylation, the apparent molecular mass of rmSELPLG/Fc monomer is approximately 82 kDa in SDS-PAGE under reducing conditions.