MW: 20,206 Da. Purity >85% (SDS-PAGE). This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3 untranslated regions. The evolutionarily conserved
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Other Names
[pumilio homolog 1 isoform 2; Pumilio homolog 1; pumilio homolog 1; pumilio RNA-binding family member 1]