Purity ~90% (SDS-PAGE). POLR2C is the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. Source: Recombinant protein corresponding to aa1-275 from human POLR2C, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~33.8kD (298aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE.