Purity > 90% as determined by SDS-PAGE. MW: 43.8kDa. Partial: 120-269aa. N-terminal GST-tagged. Homo sapiens (Human). Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory elent binding proteins (SREBPs). Can also promote apoptosis.