Recombinant Norwalk virus Capsid protein VP1 (ORF2)
Description
Purity > 90% as determined by SDS-PAGE. MW: 59.6kDa. Full Length: 1-530aa. C-terminal Flag-Myc-tagged. Norwalk virus (strain GI/Human/United States/Norwalk/1968) (Hu/NV/NV/1968/US). Capsid protein self assbles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assbled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.