Purity: > 85 % by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl.. CBX1 is a member of the heterochromatin protein family and enriched in the heterochromatin and associated with centromeres. It is recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. This protein may play an important role in the epigenetic control of chromatin structure and gene expression. Recombinant human CBX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.