FK506 Binding Protein 4, 59kDa (FKBP4) (AA 1-459) protein (His tag)
Description
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP4, 51kDa FK506-binding protein, 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4