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Description
Rat Anti-AGER Recombinant Antibody (8B42). This product is a Rat antibody that recognizes AGER. The antibody 8B42 can be used for immunoassay techniques such as: ELISA, WB. The advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
Immunogen
Recombinant corresponding to Gly23-Ala342 of mouse RAGE extracellular domain expressed in NSO cells. Accession #Q62151
Other Names
Advanced Glycosylation End-Product Specific Receptor; RAGE; Receptor For Advanced Glycation End-Products Variant 20; Advanced Glycosylation End Product-Specific Receptor; Receptor For Advanced Glycosylation End Products; Receptor For Advanced Glycation End-Products; RAGE Isoform NtRAGE-Delta; RAGE Isoform SRAGE-Delta; SCARJ1;