Recombinant Human 26S proteasome non-ATPase regulatory subunit 11 protein (PSMD11)
Description
Purity > 90% as determined by SDS-PAGE. MW: 74.3kDa. Full Length of Mature Protein: 2-422aa. N-terminal GST-tagged. Homo sapiens (Human). Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assbly. Plays a key role in increased proteasome activity in bryonic st cells (ESCs): its high expression in ESCs promotes enhanced assbly of the 26S proteasome, followed by higher proteasome activity.