A flavonoid with diverse biological activities; inhibits osteoclast differentiation, bone resorption, activation of NF-κB and NFAT by RANKL, and calcium oscillations in vitro; in vivo administration protects ovariectomized mice from bone loss; reduces lipid accumulation in HepG2 cells and reverses hyperlipidemia in a mouse model of diet-induced obesity; increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in a mouse model of diabetes,