Recombinant Human N-acetyl-D-glucosamine kinase (NAGK)
Description
Purity > 90% as determined by SDS-PAGE. MW: 53.2kDa. Full Length of Mature Protein: 2-344aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.