Growth Differentiation Factor 3 (GDF3) (Active) protein
Description
GDF-3 is a member of the TGF beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes. Alternative Names: GDF 3 protein, GDF-3 protein, GDF-3, GDF3, Growth/Differentiation Factor-3 protein, GDF-3 protein, GDF 3