Growth Differentiation Factor 6 (GDF6) (Active) protein
Description
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. Alternative Names: BMP-13 protein, BMP-13, BMP 13, CDMP-2 protein, BMP-13 protein, Cartilage-Derived Morphogenetic Protein-2 protein, Bone Morphogenetic protein 13 protein, BMP13, GDF-6 protein, BMP 13 protein