A typical antipsychotic; dopamine D2 receptor antagonist (Ki = 0.38 nM); 5-HT2A inverse agonist (Ki = 7 nM); reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine in rats at 0.5 mg/kg; inhibits acid sphingomyelinase activity by 81.8% at 10 mM