BenzAlt? Binuclease is a genetically engineered non-specific endonuclease from Serratia marcescens gene. It is a perfect alternative for Benzonase (BenzAlt? ) and is very cost effective. Functionally, this promiscuous nuclease digests all forms of DNA and RNA, including single stranded, double stranded, linear, circular and supercoiled DNA and RNA. The enzyme cleaves the phosphodiester bond of nucleic acids, producing 5' monophosphate terminated oligonucleotides 2-5 bases in length. BenzAlt? Binuclease is not a sequence dependent nuclease, capable of cleaving the phosphodiester bond at all positions among a nucleic acid chain. The enzyme is produced and purified from eukaryotic yeast cells, without contamination of endotox