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Description
Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. The D1 subtype is the most abundant dopamine receptor in the central nervous system. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.
Immunogen
Dopamine receptor 2 antibody was raised in rabbit using a 13 amino acid peptide of rat D1 R as the immunogen.