Human Glutathione Reductase DyLight? 488 conjugated
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human
Isotype
n/a
Format
DyLight?488 conjugate
Size
100ug
Concentration
0.5-1mg/ml, actual concentration varies by lot.
Applications
Flow Cytometry
Reviews / Ratings
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Description
Rabbit IgG Polyclonal Anti-Human Glutathione Reductase Antibody DyLight? 488 Conjugated, Flow Validated. No cross reactivity with other proteins. Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Immunogen
E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).