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Description
The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin α 4 β 7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The α 4 β 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.
Immunogen
AKR/Cum mouse spontaneous T lymphoma cell line TK1 1