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Description
Rabbit IgG polyclonal Picoband? antibody for Fos-related antigen 2(FOSL2) detection. Tested with WB in Human;Rat.. No cross reactivity with other proteins. Fos-related antigen 2 is a protein that in humans is encoded by the FOSL2 gene. The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human FRA2 (96-127aa ALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKR), identical to the related mouse and rat sequences.