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Description
MKK3(Ser218)/MKK6(Ser207) Antibody, FITC Conjugated. ? Target Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, w
Immunogen
KLH conjugated synthetic phosphopeptide derived from human MKK3 around the phosphorylation site of Ser218. Immunogen Range: 200-230/347