An HIV-1 integrase inhibitor (IC50 = 7.5 nM for strand transfer activity); has antiviral activity against clinical isolates of HIV-1 in PBMCs (EC50s = 0.04-1.7 nM); inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively)