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| Antigenic Specificity | IKK beta/IKBKB |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat (predicted: hamster) |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal antibody for Inhibitor of nuclear factor kappa-B kinase subunit beta(IKBKB) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. IKBKB(Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta), also known as IKKB or NFKBIKB , is a protein that in humans is encoded by the IKBKB gene. Shindo et al.(1998) mapped the IKBKB gene to chromosome 8p12-p11 by FISH. Mercurio et al.(1997) found that mutations in IKK2 had a more pronounced effect upon NFKB activation than did comparable mutations in IKK1. Yin et al.(1998) tested the activity of various antiinflammatory agents on the IKK complex. They demonstrated that aspirin and sodium salicylate specifically inhibit IKK-beta activity in vitro and in vivo by binding to IKK-beta to reduce ATP binding. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human IKK beta(588-604aa QEMVRLLLQAIQSFEKK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid. |
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| Other Names | Inhibitor of nuclear factor kappa-B kinase subunit beta;I-kappa-B-kinase beta;IKK-B;IKK-beta;IkBKB;2.7.11.10;I-kappa-B kinase 2;IKK2;Nuclear factor NF-kappa-B inhibitor kinase beta;NFKBIKB;IKBKB;IKKB; |
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| Gene, Accession # | IKBKB, UniProt: O14920 |
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| Catalog # | PA2036-1 |
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| Price | |
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| Order / More Info | IKK beta/IKBKB Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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