Purity > 90% as determined by SDS-PAGE. MW: 50kDa. Full Length: 1-204aa. N-terminal GST-tagged. Homo sapiens (Human). Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.