Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate-buffered saline (pH 7.4). Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. Recombinant human IRF3 was expressed in E.coli and purified by using conventional chromatography techniques