ELISA, Immunoprecipitation, Western Blot. This antiserum against Human IL-1 Receptor Type II (IL-1RII) has been tested for use in ELISA, radioimmunoassays and immunoprecipitation. Reactivity in other immunoassays is unknown. IL-1RII has been termed p68 or CD121 in some laboratories. IL-1RII has been shown to bind IL-1, IL-1a and IL-1b.
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Description
This antiserum is directed against the extracellular domain of the human IL-1R type II, but precipitates the intact receptor expressed on human cells. In general, this antibody also detects primate IL-1RII. The antibody does not recognize human IL-1, IL-1Ra or IL-1R type I. In ELISA formats and other immunoreactive assays, this antibody will detect the extracellular domain of the IL-1R type II (also called soluble IL-1R type II) found in human body fluids, particularly in the circulation, urine and supernatants of cells and synovial fluid.
Immunogen
This whole rabbit serum was prepared by repeated immunizations with recombinant human IL-1R type II.
Other Names
IL1RB antibody, Interleukin 1 receptor type II precursor antibody, MGC47725 antibody, p68 antibody, Type II interleukin 1 receptor beta antibody, Antigen CDw121b antibody, rabbit anti-interleukin-1 Receptor Type II Antibody