Mitochondria are essential double-membrane bound organelles that support aerobic respiration and most of the cellular ATP production in all nucleated mammalian cells. To date, hundreds of pathogenic mitochondrial DNA mutations have been identified to result in disease phenotypes such as cancer, ataxia, and diabetes. As a result, isolation of high quality mitochondrial DNA from mammalian cells and tissues in sufficient quantities is important for many basic research and clinical applications. BioVision's Mitochondrial DNA Isolation Kit facilitates purification of quality mitochondrial DNA from mammalian cultured cells or tissue. This kit utilizes a density separation step to isolate mitochondria from the rest of the cellular organelles, foll
Size
25 purifications
Concentration
n/a
Applications
PCR, cloning, DNA hybridization, southern blotting, genotyping, restriction enzyme digest analysis, sequencing, etc.