DNA was prepared from cell line WM1963. WM1963 is a human melanoma cell line that displays a melanocytic morphology and was established from a tissue sample of a 56-year-old male patient. This cell line contains a N581S mutation in BRAF gene resulting in an amino acid substitution from asparagine to serine at codon 581 (Asn581Ser) and A146T mutation in N-RAS gene resulting in a substitution of alanine with threonine at codon 146 (Ala146Thr). WM1963 cells produce xenograft tumors when injected into immunocompromised mice.
Size
25 μg
Concentration
200 ng / μl
Applications
Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis.
Other Names
Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft