A selective inhibitor of Aurora B kinase (IC50 = 10 μM), less potently inhibiting Aurora C and A (IC50 = 250 and 1,000 nM, respectively); has been used to study the role of Aurora B in molecular events associated with mitosis and cytokinesis; selectively inhibits proliferating cells rather than non-dividing cells
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
auroras A B C kinases mitosis cytokinesis centromere inhibitors inhibits inhibition cancers Benzamides