An antagonist of the EP4 receptor (Ki = 1.3 nM) that less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors; implicates EP4 signaling in immune and autoimmune responses, inflammation, and cancer
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
receptors antagonists prostaglandins PGs cancers autoimmune diseases immunology inflammation signals transductions EPs EP4 EP-4 ONO AE3 208 ONOAE3208 EP3 EP-3 three 3 FP TP prostanoids immune AE 3-208 ONO-AE3-208 402473-54-5 876155-92-9 auto-immune auto four ONO-AE-3-208 ONO sodium salts signaling responses