Toll-like receptor 7 (TLR7) agonist. Induces upregulation of IL-6, IL-12, IFN-γ and iNOS expression in mouse bone marrow-derived macrophages (BMMs). Inhibits RANKL-induced osteoclast differentiation in mouse BMMs and human peripheral blood monocytes. Also promotes the differentiation of MDSCs into macrophages and dendritic cells. Proinflammatory and antiviral. Purity 98%. MW (observed): 314.38
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol. R 848