A selective PAM of mGluR4, displaying EC50 values of 110 and 240 nM for rat and human receptors, respectively; passes the blood-brain barrier to act centrally in rats
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
biochemical receptor biochemistry signal transduction neuroscience VU-0361737 selective positive allosteric modulator mGluR4 PAM blood-brain barrier central