Purity >95% by HPLC. Pep-1 peptide is a well-known cell penetrating peptide (PTD, protein transduction domain) that transports full-length proteins to the nucleus of the cell. Pep-1 is a short amphipathic peptide consisted of a hydrophobic tryptophan-rich domain and a hydrophilic lysine-rich domain separated by a spacer. Pep-1 localizes rapidly (<10 min) to the nucleus of the cell via an endocytosis-independent internalization process. The Pep-1 peptide is able to efficiently deliver a variety of peptides and proteins in living cells in a fully biological active form.
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Other Names
Cell penetrating peptide, Pep-1, PEP1, PTD, protein transduction domain