Purity ~90% (SDS-PAGE, HPLC) Chromatographically purified. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. Source: Recombinant protein corresponding to mutant human p53, expressed in E. coli. Molecular Weight: ~81kD Endotoxin: <0.1ng/ug