An inhibitor of the Rho/MRTF/SRF transcriptional pathway; a derivative of CCG-203971; inhibits MRTF-dependent transcription in HEK293T cells (IC50 = 0.55 μM in a luciferase reporter assay); reduces expression of α-SMA in TGF-β-stimulated human dermal fibroblasts to 31% of control at 10 μM; inhibits increases in dermal thickness and hydroxyproline content in a mouse model of bleomycin-induced dermal fibrosis at 50 mg/kg