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| Antigenic Specificity | Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase) (KDR) (aa 454-469), (Middle Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KDR(Kinase Insert Domain Receptor), also known as FLK1, VEGFR or VEGFR2, is a VEGF receptor. KDR is the human gene encoding it. Sait et al.(1995) likewise corrected the assignment to chromosome 4q11-q12 to the same region occupied also by PDGFRA and KIT, thus indicating the location of a cluster of receptor tyrosine kinase genes. Vascular endothelial growth factor(VEGF) is the only mitogen that specifically acts on endothelial cells. Its expression is upregulated by hypoxia, and its cell-surface receptor, known as fetal liver kinase-1(Flk1) in mouse, is exclusively expressed in endothelial cells(Plate et al., 1993). Flk1 is the mouse homolog of KDR(Matthews et al., 1991). |
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| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human VEGF Receptor 2(454-469aa HHIHWYWQLEEECANE). |
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| Other Names | vegfr-2|KDR|6130401C07|Flk-1|Flk1|Krd-1|Ly73|VEGFR-2|VEGFR2|sVEGFR-2|Vegfr-2|CD309|FLK1|VEGFR|FLK-1|flk-1|FLK/KDR|flk1|flk1b|kdrb|si:busm1-205d10.1|si:ch211-254j6.1|si:ch211-278f21.4|wu:fc31a09|fk52c05|flk|kdr|kdra|vegfr2|vegfr4|vegr2|wu:fk52c05 |
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| Gene, Accession # | Gene ID: 3791 |
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| Catalog # | ABIN1673472 |
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| Price | |
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| Order / More Info | Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase) (KDR) (aa 454-469), (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 7736781, 1717995, 7694795 |
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