A cell-permeable inhibitor of the dimerization of c-Myc and Max at 64 μM, preventing c-Myc-dependent gene expression and cell proliferation; induces cell cycle arrest, apoptosis, and myeloid differentiation at 100 μM in human acute myeloid leukemia cells; inhibits the nuclear Myc protein, N-Myc, at 50 μM
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
cancers apoptosis genes regulations transcription factors oncogenes Myc Max dimer regulates proteins c-Myc cells growth 10058F4 10058 F4 permeable thiazolidione inhibits inhibition inhibitors proliferation cycles arrest myeloid humans leukemia metabolized metabolism mice tumors in vivo nuclear neuroblastoma n-Myc n c lipids glucose