Insulin-Like Growth Factor 1 (IGF1) (AA 1-115) (Active) protein
Description
The Insulin-like growth factor-1(IGF-1) is a mitogenic polypeptide growth factors that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1s are similar in structure and function to insulin, but have a much higher growth-promoting activity than insulin. This recombinant human IGF-I is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds. Recombinant IGF-1 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Alternative Names: MGF protein, IGF 1 protein, IGF-IA protein, Insulin like growth factor 1 protein, Insulin like growth factor 1 (somatomedin C) protein, Insulin like growth factor IB protein, IGF1 protein, IGFI protein, IGF IB protein, IGF1, IGF-1, IGF 1, IBP1 protein, IGF-1 protein, Insulin-like growth factor-1 protein, IGF1 protein, Mechano growth factor protein, IGF-1 protein, , Somatomedin C protein, IGFIA protein, Insulin like growth factor IA protein, Insulin-like growth factor-1 IGF IA protein, IBP1 protein, Somatomedin-C protein