TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL7 and binds with the heterodimeric receptor complex consisting of the IL7R alpha chain (IL7Ra) and the TSLP-specific chain (TSLPR). Like IL7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). Alternative Names: Thymic Stromal Lymphopoietin protein, TSLP protein