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Description
DTNBP1 Polyclonal Antibody, Alexa Fluor? 488 Conjugated. ? Target Background: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex
Immunogen
KLH conjugated synthetic peptide derived from human DTNBP1. Immunogen Range: 130-180/351