Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
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Description
MAP4K2 Polyclonal Antibody. The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Immunogen
n/a
Other Names
Mitogen-activated protein kinase kinase kinase kinase 2; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; Germinal center kinase; GC kinase; Rab8 interacting protein; B lymphocyte serine/threonine-protein kinase