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| Antigenic Specificity | MAPK15 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAPK15 Polyclonal Antibody. The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions. |
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| Immunogen | n/a |
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| Other Names | Extracellular signal-regulated kinase 8; MAPK15; Mitogen-activated protein kinase 15 |
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| Gene, Accession # | Entrez: 225689; Uniprot: Q8TD08 |
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| Catalog # | PA5-14488 |
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| Price | |
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| Order / More Info | MAPK15 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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