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Description
Rabbit monoclonal antibody to detect p38 MAPK in human samples. p38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cell cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.