Protein G Magnetic Beads are prepared by covalently coupling Recombinant Protein G (contains three IgG binding domain, BV catalog # 6510-10) to 6% crosslinked magnetically beaded agarose. The coupling technique is optimized to give a high binding capacity for IgG. The capacity of IgG binding is generally greater than 15 mg of rabbit IgG per ml of wet gel.