Cysteinyl leukotriene receptor 1 (CysLT1) and GPR17 antagonist. Blocks pentylenetetrazole -induced seizures, blood brain barrier (BBB) disruption and leukocyte migration in mice. Reduces neuroinflammation, improves BBB integrity, enhances learning and memory, and restores hippocampal neurogenesis and cognitive function in aged rats. Orally active and brain penetrant. Purity 99%. MW (observed): 608.17
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt