Flow Cytometry, Immunohistochemistry, Western Blot
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Description
Antigen: human caspase-8 amino acids PVETDSEEQP ? Host: mouse, clone 90A992 ? Isotype: IgG1 ? Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8 ? Application(s): FC, IHC (paraffin-embedded tissue), and WB ? Caspase-8 forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.
Immunogen
human caspase-8 amino acids PVETDSEEQP
Other Names
caspases eight 8 cysteine proteases key mediators programmed cells death apoptosis FLICE ICE CD95 CD-95 CDs 95 subunits a2be active enzyme inhibitors inhibits inhibition antibodies western blots blotting immunoblotting WB immunohistochemistry IHC flow cytometry FC