Immunohistochemistry (Paraffin): Assay Dependent, Western Blot: 1/500 - 1/1000
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Description
Amyloid Precursor Protein Polyclonal Antibody. Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.